Morphospace / Conversation #1 with Diego Bohórquez and Mijail D. Serruya: How Information Moves Levels in Bodies

Conversation #1 with Diego Bohórquez and Mijail D. Serruya: How Information Moves Levels in Bodies

In one paragraph

A gut-brain neuroscientist and a neurologist-engineer talk with Levin about how information crosses levels — from gut sensor cells to the brain, and from neurons in a dish to clinical tools.

Main ideas (plain words)

  • Bohórquez's lab found gut sensor cells wired to the vagus nerve that rapidly sense nutrients and signal the brain to guide decisions.
  • Serruya grows rat and human neurons on 2D and 3D electrode arrays and asks how a clinician can 'talk' to cells in a language they respond to.
  • Levin's frame: much information may be unavailable only because we lack the right interface; hypnosis and similar methods might soften the boundaries between levels.
  • His lab is already trying to put a language layer on top of biology — talking to gene regulatory networks in English — with some success.
  • Next step he proposes: each writes down minimal models that would answer one shared question.

Why it matters

This is the interface question in its most practical form, and the language-layer idea is where LLM agents and Levin's biology meet.

Key quotes (word for word from YouTube's auto-generated captions)

Quotes are copied exactly from the captions, including filler words and caption errors. Timestamps are to the nearest minute.

"we have a system that's very good at doing things and knowing things and not great at talking about it"
— 48 min

"trying to talk to gene regulatory networks in English"
— 48 min

"I think we should go off and each of us writes down one or more uh minimal minimal models"
— 54 min

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